EDIT
The region under the greatest stress is the Great Plains, an area from North Dakota to Texas dubbed the Great American Desert by early explorers but turned into a garden spot in the last century thanks to a single innovation: irrigation.
But farmers from Nebraska through northern Texas are now growing more water-thirsty crops, like corn, that offer them better cash returns due to changing trends such as the boom in ethanol and biodiesel fuels. That is only accelerating the depletion of ground water faster than it can be replenished by rain. In some cases, farm land is already being idled to conserve water.
"My sense in looking at these issues for 20 years, we're going to need at least a doubling of water productivity in agriculture if we're going to have an opportunity to meet food demand in a way that is somewhat environmentally sustainable," said Sandra Postel with the Global Water Policy Project, a group in Amherst, Massachusetts that analyzes water policies.
EDIT
But U.S. water problems have the greatest implications for world food supplies. The United States for decades has been the planet's "food reserve," the top exporter of wheat, corn and soybeans and the largest single provider of food aid to other nations. The squeeze on water for U.S. farms is pushing innovation, such as a trend away from flood irrigation to center pivot sprinklers or state-of-the art, localized drip irrigation. "Just the changing of irrigation techniques can save a lot of water. That's the first place to start," said Thomas Kimmell, executive director with the Irrigation Association.
EDIT
http://www.enn.com/today.html?id=11114