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whopis01 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 11:33 AM
Original message
Lancet accepts MMR study 'false'
Source: BBC News

The medical journal which originally published the discredited research linking autism and MMR has now issued a full retraction of the paper.

It comes after Dr Andrew Wakefield, the lead researcher in the 1998 paper, was ruled last week to have broken research rules by the General Medical Council.

But they accepted that in hindsight they may not have been, after accusations of a conflict of interest - Dr Wakefield was in the pay of solicitors who were acting for parents who believed their children had been harmed by MMR.

But this move goes further by accepting the research was fundamentally flawed because of a lack of ethical approval and the way the children's illnesses were presented.

Read more: http://news.bbc.co.uk/2/hi/health/8493753.stm
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joeybee12 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 11:36 AM
Response to Original message
1. Good...can we put Jenny McCarthy into prison now?
:shrug:
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Fumesucker Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 11:39 AM
Response to Reply #1
2. I hate this namby pamby, half measures shit, she should be executed..
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Iggo Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 12:03 PM
Response to Reply #2
4. But she has an excellent rack!
Where the fuck are you people's priorities?

GAH!
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BrightKnight Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 11:33 PM
Response to Reply #4
27. Her body count is more than 150 Dead and 17,268 ill. - n/t
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Iggo Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-04-10 09:57 AM
Response to Reply #27
29. 38-24-34..I like my numbers better.
:9
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woo me with science Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 11:57 AM
Response to Original message
3. Good. nt
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LeftyMom Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 12:07 PM
Response to Original message
5. Took them long enough.
Edited on Tue Feb-02-10 12:08 PM by LeftyMom
:time to lurk in Health: :popcorn:
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Iggo Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 12:09 PM
Response to Reply #5
6. That sounds like fun.
:popcorn:
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LeftyMom Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 12:28 PM
Response to Reply #6
7. Still no thread about it.
Strange, considering there are five dupe threads nodding along in agreement if Jenny McCarthy has cornflakes for breakfast or that quack Mercola has a new post up about baking soda curing swine flu. Surely the anti-science weirdos aren't avoiding contradictory evidence, are they? :rofl:

Maybe the news just hasn't broken yet in the alternate universe where the MMR causes teh autism and megadoses of vitamin D cure it.
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TrogL Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 02:52 PM
Response to Reply #7
8. They'll just switch causes
It'll be high voltage power lines causing autism and iron lungs to cure it.
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TheWraith Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 03:06 PM
Response to Original message
9. Kick and rec for junk science getting smacked down.
And a kick in the ass for all the people who are going to call me a shill for Big Pharma now. :eyes:
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EFerrari Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 03:31 PM
Response to Original message
10. Can someone decode this sentence for me please? They may not have been what?
Edited on Tue Feb-02-10 03:32 PM by EFerrari
"But they accepted that in hindsight they may not have been, after accusations of a conflict of interest - Dr Wakefield was in the pay of solicitors who were acting for parents who believed their children had been harmed by MMR."

ETA: I see. The snip was not marked. Whew! Never mind.
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Odin2005 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 04:34 PM
Response to Original message
11. About fucking time.
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alp227 Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 05:15 PM
Response to Original message
12. This cuts off the anti-vaxers' legs fo sho
I get tired of hearing people complain "my kid is anti-social cuz of vaccines". The majority of vaccinated people I've met are sane alright.
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Posteritatis Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 09:32 PM
Response to Reply #12
13. Eh, they'll just get prosthetics. (nt)
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Book Lover Donating Member (1000+ posts) Send PM | Profile | Ignore Tue Feb-02-10 11:54 PM
Response to Original message
14. Kick for the truth, and for my spectrum child
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Prometheus Bound Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 12:39 AM
Response to Original message
15. Looking at it from a different perspective..... (Now don't get angry.)
Wakefield's reaction
Wakefield continues to defend his work and now works at Thoughtful House, a treatment centre for children with developmental disorders, in Austin, Texas.

"The allegations against me and against my colleagues are both unfounded and unjust, and I invite anyone to examine the contents of these proceedings and come to their own conclusion," Wakefield said in a statement provided by Thoughtful House.
http://www.ctv.ca/servlet/ArticleNews/story/CTVNews/20100202/vaccine_100202/20100202/?hub=TopStoriesV2

The Lancet Retraction Changes Nothing
David Kirby
Dr. Andrew Wakefield is one of the most vilified medical practitioners of recent times, and now he carries the extremely rare dishonor of a retraction in The Lancet, on the paper he coauthored in 1998 suggesting a potential link between autism, bowel disease and Measles-Mumps-Rubella (MMR) vaccine.

I believe that the public lynching and shaming of Dr. Wakefield is unwarranted and overwrought, and that history will ultimately judge who was right and who was wrong about proposing a possible association between vaccination and regressive autistic spectrum disorder (ASD).

Wakefield's critics can condemn, retract, decry and de-license all they want, but that does nothing to stop or alter the march of science, which has come a long way over the past 12 years, and especially in the last year or two. The evidence that autism is increasing at alarming rates, and that some thing (or things) in our environment is wreaking havoc on a vulnerable one-percent of all US children is now so irrefutable that, finally, the federal government is climbing aboard the environmental research bandwagon - way late, but better than never.

This long-overdue paradigm shift will leave many in the scientific community with some proverbial but nonetheless uncomfortable egg on their increasingly irrelevant faces: Those who have protested with shrill certainty that autism is almost purely genetic, and not environmental in nature, and therefore not really increasing at all, will hopefully recede from the debate.

And that begs a nagging question: If those people were dead wrong about environmental factors in autism, could they also be mistaken in their equally heated denials about a possible vaccine-autism link? More bluntly, why should we heed them any longer?
http://www.huffingtonpost.com/david-kirby/the-emlancetem-retraction_b_446749.html

Local Mother Speaks out About Autism and the MMR Vaccine
At least 1 in 110 children have autism, and while several factors could be to blame, one local mother is outraged about the ground-breaking article being retracted. She says she knows her son has autism because of the MMR vaccine.

Nancy Jackson says her son, Cole, was a healthy newborn baby. "Nothing was wrong, he was perfect, then, he had his MMR, and the lights went out." She remembers the last sentence Cole spoke at the age of two. "Daddy I need another shoe, or daddy I need a shoe, and that was the last sentence we ever heard him say, because then he had his MMR, and literally from one day to the next he was a different child, and he, the jirations, and the out of world look he had, and the constant stemming, he couldn't sleep, it was a different child, it was watching your child go away from you in front of your eyes but him still be there physically."

"We have a couple of parents that work with our program that have already feel very strongly that the mmr shots have had an impact on their child's life," said Dr. Marty Boman, the director of the Kelly Autism Center in Bowling Green says there's an ongoing dispute over the effect of heavy metal poisoning from immunizations, and autism. "There have been multiple studies on this," said Boman, "a lot of them disproving, a lot of them saying that it's supportive of everything, and it's difficult because everyone of them is using different criteria."
http://www.wbko.com/news/headlines/83411557.html

Iowans React To Retracted Study Linking Vaccines To Autism
.....Some Central Iowa parents of autistic children still believe there could be a link between vaccines and autism.

Danielle Sharpe’s son, Spencer, was diagnosed with autism at the age of 3. She wonders what role, if any, vaccines might have played.

Danielle Sharpe said, “I don't know that it caused my son's autism, but I have friends who are confident that their child was vaccinated and starting later that day or the next day it all started going downhill.”
http://www.kcci.com/news/22417203/detail.html

Autism Vaccine Link Refuted; Some Parents Not Convinced
.....Still, many parents like Lisa Rupe are unconvinced. Her son, Kyle, has autism. She's not sure his autism stems from vaccines, but she believes the shots have caused autism in others. She stopped her younger child's vaccinations as a precaution.

Rupe is frustrated by what she sees as a dismissive attitude of scientists toward concerned parents.

"You saw your child slip away right before your eyes. It's not something you can just write off," she says.

Rupe believes the doctors behind the vaccine study are backing off their research because of severe pressure from the medical community and companies that make vaccines. She won't be satisfied until science finally finds the cause of autism and effective treatement.

"Something in our environment is giving our kids autism and we don't know what it is."
http://www.620wtmj.com/news/local/83408752.html

Retraction Of Some Research Doesn’t Deter Parent Who Believes In Link Between Vaccine And Autism
The topic of vaccines and autism is always controversial and the retraction on Tuesday of Dr. Andrew Wakefield’s study will likely do little to calm it. Kim Spencer is the parent of an autistic child who also works in a local pediatrician’s office. She doesn’t mince words when she talks about what she believes was the cause of her son’s autism. She lays the blame on a vaccine he was given at the age of two…and nothing that’s happened regarding Dr. Wakefield’s work is going to change her mind.

Her son is 9 years old now and was diagnosed with autism about 7 years ago. Spencer doesn’t believe the Measles/Mumps/Rubella vaccine is to blame, but thinks another vaccine was. She has heard Dr. Wakefield speak and says the ethical concerns about his research don’t change her opinion, “There’s nothing in this decision that says at all that MMR can’t be linked to autism in the future or that vaccines don’t have anything to do with autism.” In fact, signs of a link between gastrointestinal illnesses and autism have been found by other researchers…though not necessarily a specific link to the MMR vaccine; but Spencer believes a memo sent to doctors just two weeks ago backs up the link first examined in Dr. Wakefield’s research, “The American Academy of Pediatrics sent out a request to their pediatricians saying that it is a trend that gastrointestinal issues show up in children with autism quite often and that it’s time for pediatricians to start paying attention to those gastrointestinal issues and also trying to treat them.”

It’s treatment of those issues she credits with helping improve her son’s autistic symptoms.
With incidents of autism on the rise in this country - the dialogue, and controversy, is sure to continue as parents and researchers look for a cause.
http://www2.wsav.com/sav/news/science/health_med_fit/article/retraction_of_some_research_doesnt_deter_parent_who_believes_in_link_betwee/93248/
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LeftyMom Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 12:54 AM
Response to Reply #15
16. That he's managed to misinform many parents who desparatly want an explanation isn't evidence
for his claim. The science is quite clear, as many studies have now been done showing there's no relationship between the MMR and autism.

The reason so many of those parents are convinced the shot caused the problem is that the shot is given at the age where autism symptoms tend to diverge sharply from typical development, as typical children's language and social skills expand rapidly and autistic children's skills do not and frequently seem to regress. This is the case regardless of a child's vaccination status. Assuming that one causes the other makes no more sense than assuming that spending all of one's money at the Hello Kitty store causes early symptoms of puberty, since both tend to happen at about age ten in American girls. Though with a hand-picked sample of a dozen kids, I could probably "prove" that the Sanrio Corporation causes puberty, just as Wakefield "proved" that the MMR causes autism. I wouldn't even have to stick a scope in a kid at their birthday party to do it.
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Spider Jerusalem Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 01:32 AM
Response to Reply #15
17. Sorry.
But no matter how many parents 'just know' that vaccination MUST BE why they have an autistic child, it still isn't so. Correlation is not causation; autism first becomes EVIDENT at approximately the same age as children receive vaccinations. This does not mean that the vaccinations caused the autism (and there have been countless population studies that have not only utterly failed to find any link whatever but have found no difference in prevalence in populations born before the introduction of the MMR vaccine and after). The neurological differences present in autistic spectrum disorders...including differences not only in brain size, but in cerebral structures and proportion of white matter to grey matter...are of such a degree, and such a kind, that they can only have their origin at a relatively early point in gestation.
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Lithos Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Feb-07-10 02:49 AM
Response to Reply #17
38. +1
Good summary.

L-

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Book Lover Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 03:09 AM
Response to Reply #15
23. I am truly grateful that these parents are a minority, loud as they are
I've met many dozens, if not a few hundred, fellow parents and primary caregivers of kids on the spectrum since my child was diagnosed, and not a one has ever asserted the vaccines-cause-autism meme. The media emphasis on these folks (to whose families I wish nothing but good things) makes it seem as if there are more than there are.
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Odin2005 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 09:10 AM
Response to Reply #15
24. Kirby, another fraud who sould be in jail.
Fuck that BS.
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hunter Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 10:32 AM
Response to Reply #15
25. Your post demonstrates just how the media is also responsible for this reprehensible crap.
Crappy science and medical reporting by dim witted know-nothings reporting the vapid and ill-informed thoughts of other know-nothings kills and maims people.

There are not "two sides" to every controversy. Every informed view does not have to be countered and obscured in a blizzard of ill-informed crap.
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Starbucks Anarchist Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 01:59 AM
Response to Original message
18. Medical journal retracts study linking autism to vaccine
Source: CNN

(CNN) -- The medical journal The Lancet on Tuesday retracted a controversial 1998 paper that linked the measles, mumps and rubella (MMR) vaccine to autism.

The study subsequently had been discredited, and last week, the lead author, Dr. Andrew Wakefield, was found to have acted unethically in conducting the research.

The General Medical Council, which oversees doctors in Britain, said that "there was a biased selection of patients in The Lancet paper" and that his "conduct in this regard was dishonest and irresponsible."

The panel found that Wakefield subjected some children in the study to various invasive medical procedures such as colonoscopies and MRI scans. He also paid children for blood samples for research purposes at his son's birthday party, an act that "showed a callous disregard" for the "distress and pain" of the children, the panel said.

Read more: http://www.cnn.com/2010/HEALTH/02/02/lancet.retraction.autism/index.html?hpt=T1



(Much more at link)
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uppityperson Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 01:59 AM
Response to Reply #18
19. Gee. k&r.
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Soylent Brice Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 01:59 AM
Response to Reply #18
20. K&R
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LeftyMom Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 01:59 AM
Response to Reply #18
21. dupe
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Posteritatis Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 01:59 AM
Response to Reply #18
22. Now they just need to revoke his license. (nt)
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provis99 Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 04:33 PM
Response to Original message
26. this won't stop the anti-vaccine nuts at all; if fact, they'll get worse.
Now they'll be shouting about a government cover-up of the "truth" of vaccine damage. Thanks for nothing, Lancet.
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neverforget Donating Member (1000+ posts) Send PM | Profile | Ignore Wed Feb-03-10 11:45 PM
Response to Original message
28. Kick for Science!
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Prometheus Bound Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-04-10 10:04 AM
Response to Original message
30. Autism link with MMR jab 'a possibility', says researcher
Consultant to the Espa Autism Research Unit
10:13am Thursday 4th February 2010

A NORTH-EAST researcher who has long suspected a link between the MMR triple vaccine and autism has said he still thinks there is “a possibility” that his team will find evidence of a connection.

Paul Shattock, scientific consultant to the Espa Autism Research Unit, in Sunderland, has spent the past decade analysing thousands of urine samples from people with autism.

He believes that the prime suspect for the steady increase in autism cases in the UK is exposure to organophosphates contained in modern pesticides.

But Mr Shattock, who recently received an OBE after founding the Education and Services for People with Autism (Espa) charity, still suspects there may be a link between a small minority of autism cases and the MMR triple vaccine for measles, mumps and rubella, despite the recent controversy surrounding Dr Andrew Wakefield.

.....“We are not saying that there definitely is a link, we are just saying we should find out,” said Mr Shattock, who founded Espa after his son was diagnosed with autism.

He dismissed the GMC verdict on Dr Wakefield as a political decision, pointing out that no one had actually made a complaint.

Mr Shattock’s suspicion of a link between MMR and autism for a minority of cases was roused in 2002 when he noticed that about one in ten parents donating urine samples to his research team said they believed the MMR jab may have triggered autism.

Eight years and thousands of urine samples later, the former pharmacy lecturer says that about six to seven per cent of parents who submit samples still claim their child’s condition was triggered by the triple vaccine.

Mr Shattock stressed that his researchers were much more interested in organophophates than finding evidence of a link with MMR, but said there was a possibility they might find evidence implicating the triple jab......
http://www.thenorthernecho.co.uk/news/4889878.Autism_link_with_MMR_jab____a_possibility___/
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BrightKnight Donating Member (1000+ posts) Send PM | Profile | Ignore Thu Feb-04-10 05:17 PM
Response to Reply #30
31. smoking is possibly good for you and the moon is possibly made of cheese.
Has he published a peer reviewed paper in a reputable journal?

As of 3/2009 150 kids were dead and 17,268 became seriously ill.
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Fool Count Donating Member (878 posts) Send PM | Profile | Ignore Thu Feb-04-10 07:12 PM
Response to Original message
32. In a related story,
the study estimating over 650,000 excess deaths due to Iraq invasion is still valid.
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Prometheus Bound Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Feb-06-10 03:00 AM
Response to Original message
33. A Statement from Jenny McCarthy & Jim Carrey: Andrew Wakefield, Scientific Censorship & 14 monkeys
Los Angeles, February 5, 2010

Dr. Andrew Wakefield is being discredited to prevent an historic study from being published that for the first time looks at vaccinated versus unvaccinated primates and compares health outcomes, with potentially devastating consequences for vaccine makers and public health officials.

It is our most sincere belief that Dr. Wakefield and parents of children with autism around the world are being subjected to a remarkable media campaign engineered by vaccine manufacturers reporting on the retraction of a paper published in The Lancet in 1998 by Dr. Wakefield and his colleagues.

The retraction from The Lancet was a response to a ruling from England’s General Medical Council, a kangaroo court where public health officials in the pocket of vaccine makers served as judge and jury. Dr. Wakefield strenuously denies all the findings of the GMC and plans a vigorous appeal.

Despite rampant misreporting, Dr. Wakefield’s original paper regarding 12 children with severe bowel disease and autism never rendered any judgment whatsoever on whether or not vaccines cause autism, and The Lancet’s retraction gets us no closer to understanding this complex issue.

Dr. Wakefield is one of the world’s most respected and well-published gastroenterologists. He has published dozens of papers since 1998 in well-regarded peer-reviewed journals all over the world. His work documenting the bowel disease of children with autism and his exploration of novel ways to treat bowel disease has helped relieve the pain and suffering of thousands of children with autism.

......Behind the scenes, the pressure to keep the work of Dr. Wakefield and his colleagues from being published is immense, and growing every day. Medical journals take extreme risk of backlash in publishing any studies that question the safety of the vaccination program, no matter how well-designed and thorough the research might be. Neurotoxicology, a highly-respected medical journal, deserves great credit for courageously publishing the first phase of this vaccinated monkey study.

The press has been deeply misled in the way The Lancet retraction, and Dr. Wakefield’s mock trial, have been characterized. Led by the pharmaceutical companies and their well-compensated spokespeople, Dr. Wakefield is being vilified through a well-orchestrated smear campaign designed to prevent this important new work from seeing the light of day.

What medical journal would want to step in front of this freight train? Moreover, why now, after 12 years of inaction, did The Lancet and GMC suddenly act? Is it coincidence that the monkey study is currently being submitted to medical journals for review and publication?

http://www.ageofautism.com/2010/02/a-statement-from-jenny-mccarthy-jim-carrey-andrew-wakefield-scientific-censorship-and-fourteen-monke.html
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Odin2005 Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Feb-06-10 12:16 PM
Response to Reply #33
34. That used up porn star needs to STFU
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WriteDown Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Feb-06-10 12:23 PM
Response to Reply #33
35. This can't be for real. Maybe breast implants cause autism or at least mental retardation. nt
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neverforget Donating Member (1000+ posts) Send PM | Profile | Ignore Sat Feb-06-10 01:55 PM
Response to Reply #33
36. Ah jeez!
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TrogL Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Feb-07-10 02:07 AM
Response to Reply #33
37. Lemme get this straight
Dr. Wakefield’s original paper regarding 12 children with severe bowel disease and autism never rendered any judgment whatsoever on whether or not vaccines cause autism

So what, exactly, was she basing her campaign on? If he isn't supporting her position, why does she care what happens to him?

He has published dozens of papers since 1998 in well-regarded peer-reviewed journals all over the world.

Name 3.

Neurotoxicology, a highly-respected medical journal


Ha. Ha-ha. Oh dear God :rofl::rofl::rofl::rofl::rofl::rofl::rofl::rofl:
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Prometheus Bound Donating Member (1000+ posts) Send PM | Profile | Ignore Sun Feb-07-10 03:23 AM
Response to Reply #37
39. Here's a few:
Key Publications by Wakefield/O’Leary groups http://www.whale.to/a/a1.html

1. Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, et al. Ileal LNH, non-specific colitis and pervasive developmental disorder in children. Lancet 1997; 351: 637-641.

2. Wakefield AJ, Anthony A, Murch SH, Thomson M, Montgomery SM, Davies S, et al. Enterocolitis in children with developmental disorder. American Journal of Gastroenterology 2000; 95:2285-2295

3. Furlano RI, Anthony A, Day R, Brown A, McGavery L, Thomson MA, et al. Colonic CD8 and ?d T cell infiltration with epithelial damage in children with autism. Journal of Pediatrics 2001;138: 366-372

4. Torrente F, Machado N, Ashwood P, et al. Enteropathy with T cell infiltration and epithelial IgG deposition in autism. Molecular Psychiatry 2002;7: 375-382

5. Uhlmann V., Martin CM., Shiels O., Pilkington L., Silva I., Lillalea A. Murch SH., Wakefield AJ., O’Leary JJ. Potential viral pathogenic mechanism for new variant inflammatory bowel disease. Molecular Pathology. 2002;55: 1-6

6. Kawashima H., Takayuki M., Kashiwagi Y., Takekuma K., Hoshika A., Wakefield AJ. Detection and sequencing of measles virus from peripheral blood mononuclear cells from patients with inflammatory bowel disease and autism. Digestive Diseases and Sciences. 2000;45: 723-729

7. Wakefield AJ and Montgomery SM. Measles, mumps, rubella vaccine: through a glass, darkly. Adverse Drug Reactions & Toxicological Reviews 2000;19:265-283.

8. Wakefield AJ and Montgomery SM. Autism, viral infection and measles mumps rubella vaccination. Israeli Medical Association Journal 1999;1: 183-187

9. Wakefield AJ, Puleston J., Montgomery SM., Anthony A., O’Leary JJ., Murch SH. Review article: the concept of entero-colonic encephalopathy, autism and opioid receptor ligands. Alimentary Pharmacology and Therapeutics 2002; 16: 663-674

10. Shiels O., Smyth P., Martin C., O’Leary JJ. Development of an allelic discrimination type assay to differentiate between strain origins of measles virus detected in intestinal tissue of children with ileocolonic lymphonodular hyperplasia and concomitant developmental disorder. Pathological Society of Great Britain and Ireland. Journal of Pathology. 2002 .A20

11. Wakefield AJ, Anthony A. Clinical characteristics of children with autism and entero-colitis comparing recipients of one and more than one measles-containing vaccine (submitted).



Publications http://www.thoughtfulhouse.org/publications.php

2009

* Hewitson L, Houser LA, Stott C, Sackett G, Tomko JL, Atwood D, Blue L, White ER and Wakefield AJ.
Delayed Acquisition of Neonatal Reflexes in Newborn Primates Receiving a Thimerosal-Containing Hepatitis B Vaccine: Influence of Gestational Age and Birth Weight. Neurotoxicology. 2009 Oct 2.

* Russo, A.J., Krigsman A, Jepson B, and Wakefield
Generalized Autoimmunity Related to Severity of Disease in Autistic Children With GI Disease. Immunology and Immunogenetics Insights 2009: 1

* Russo, A.J., Krigsman A, Jepson B, and Wakefield A.
Low Serum Myeloperoxidase in Autistic Children With GI Disease. Clinical and Experimental Gastroenterology, 2009: 2, 85-94.

* Russo, A.J., Krigsman A, Jepson B, and Wakefield A.
Low Serum Alpha-1 Antitrypsin Associated with Anti-PR-3 ANCA in Autistic Children With GI Disease. Genomics Insights, 2009: 2, 1-9.

* Russo,A.J., Krigsman A, Jepson B and. Wakefield A
Anti-PR3 and Anti-MPO IgG ANCA in Autistic Children With Chronic GI Disease, Immunology and Immunogenetics Insights, 2009: 1, 21-28.

* Wakefield AJ, Blaxill M, Haley B, Ryland A, Hollenbeck D, Johnson J, Moody J and Stott C
Response to Dr. Ari Brown and the Immunization Action Coalition. Medical Veritas 6, 2009: 1907-1924.

2008

* Wakefield AJ, Stott C, Krigsman A.
Arch Dis Child. 2008 Oct;93(10): 905-6; author reply 906-7. No abstract available. Pubmed

2006

* Ashwood P, Wakefield A.
Immune activation of peripheral blood and mucosal CD3+ lymphocyte cytokine profiles in children with autism and gastrointestinal symptoms. Journal of Neuroimmunology: 2006 Feb 20.

* Wakefield A, Stott C, Limb K.
Gastrointestinal comorbidity, autistic regression and Measles-containing vaccines: positive re-challenge and biological gradient. Medical Veritas: 3 (2006) 796-802.

2005

* Wakefield AJ, Ashwood P, Limb K, Anthony A.
The significance of ileo-colonic lymphoid nodular hyperplasia in children with autistic spectrum disorder. European Journal of Gastroenterology and Hepatology 2005 : 17

2004

* Ashwood P, Anthony A, Torrente F, Wakefield AJ.
Spontaneous mucosal lymphocyte cytokine profiles in children with regressive autism and gastrointestinal symptoms: Mucosal immune activation and reduced counter regulatory interleukin-10. Journal of Clinical Immunology. 2004:24:664-673

* Bradstreet JJ., El Dahr J., Anthony A., Kartzinel J., Wakefield AJ
Detection of Measles Virus Genomic RNA in Cerebrospinal Fluid of Children with Regressive Autism: a Report of Three Cases Journal of American Physicians and Surgeons. 2004.9:39-45

* Stott C., Blaxill M., Wakefield AJ.
MMR and Autism in Perspective: the Denmark Story. Journal of American Physicians and Surgeons 2004;9:89-91

* Wakefield AJ, Harvey P, Linnell J.
MMR--responding to retraction. Lancet. 2004 Apr 17;363(9417): 1327-8; discussion 1328. No abstract available.

2003

* Ashwood P, Anthony A, Pellicer AA, Torrente F, Wakefield AJ.
Intestinal lymphocyte populations in children with regressive autism: Evidence for extensive mucosal immunopathology. Journal of Clinical Immunology, 2003;23 : 504-517.

* Wakefield AJ.
Measles, mumps, and rubella vaccination and autism. N Engl J Med. 2003 Mar 6;348(10): 951-4; author reply 951-4. No abstract available.

2002

* Wakefield AJ.
The New Autism (Invited Article) Clinical Child Psychology & Psychiatry 2002;7: 518-528

* Wakefield AJ., Puleston J. Montgomery SM., Anthony A., O'Leary J.J., Murch SH
Entero-colonic encephalopathy, autism and opioid receptor ligands. Alimentary Pharmacology & Therapeutics. 2002;16:663-674

* Torrente F., Machado N., Perez-Machado M., Furlano R., Thomson M., Davies S., Wakefield AJ, Walker-Smith JA, Murch SH.
Enteropathy with T cell infiltration and epithelial IgG deposition in autism. Molecular Psychiatry. 2002;7:375-382

* Wakefield AJ.
The Gut-Brain Axis in Childhood developmental Disorders. Journal of Pediatric Gastroenterology and Nutrition. 2002;34:S14-S17

* Uhlmann V., Martin C, Shiels, Wakefield AJ, O.Leary JJ.
Possible viral pathogenesis of a novel paediatric inflammatory bowel disease. Molecular Pathology 2002;55:84-90

* Wakefield AJ.
Enterocolitis, autism and measles virus. Molecular Psychiatry. 2002;7: S44-46

* Wakefield AJ.
Entero-colitis, Autism and Measles Virus. Consensus in Child Neurology. 2002;6: 74-77 Journal

* Torrente F, Ashwood P, Day R, Machado N, Furlano RI, Anthony A, Davies SE, Wakefield AJ, Thomson MA, Walker-Smith JA, Murch SH.
Small intestinal enteropathy with epithelial IgG and complement deposition in children with regressive autism. Mol Psychiatry. 2002;7(4): 375-82, 334.


2001

* Furlano RI, Anthony A, Day R, Brown A, McGavery L, Thomson MA, Davies SE, Berelowitz M, Forbes A, Wakefield AJ, Walker-Smith JA, Murch SH.
Colonic CD8 and gamma delta T-cell infiltration with epithelial damage in children with autism. Journal of Pediatrics 2001;138: 366-72.

2000

* Wakefield AJ, Anthony A, Murch SH, Thomson M, Montgomery SM, Davies S, Walker-Smith JA.
Enterocolitis in children with developmental disorder. American Journal of Gastroenterology 2000;95: 2285-2295

* Kawashima H., Takayuki M., Kashiwagi Y., Takekuma K., Hoshika A., Wakefield AJ.
Detection and sequencing of measles virus from peripheral blood mononuclear cells from patients with inflammatory bowel disease and autism. Digestive Diseases and Sciences. 2000;45: 723-729

* Wakefield AJ and Montgomery SM.
Measles, mumps, rubella vaccine: through a glass, darkly. Adverse Drug Reactions & Toxicological Reviews 2000;19: 265-283

* O'Leary JJ, Uhlmann V, Wakefield AJ.
Measles virus and autism. Lancet. 2000;356: 772 (letter)

1999

* Wakefield AJ and Montgomery SM.
Autism, viral infection and measles mumps rubella vaccination. Israeli Medical Association Journal 1999;1: 183-187

* Montgomery SM, Morris DL, Pounder RE, Wakefield AJ
Paramyxovirus infections in childhood and subsequent inflammatory bowel disease. Gastroenterology 1999;116: 796-803

* Wakefield AJ.
MMR vaccination and autism. Lancet. 1999;354: 949-50 (letter)

1998

* Wakefield AJ, Murch SH, Anthony A, Linnell J, Casson DM, Malik M, Berelowitz M, Dhillon AP, Thomson MA, Harvey P, Valentine A, Davies SE, Walker-Smith JA
Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet 1998 Feb 28;351(9103): 637-41

Oral, Poster Presentations, and Book Chapters

* Hewitson L, Lopresti B, Stott CM, Tomko J, Houser LA, Klein E, Castro CA, Sackett G, Gupta S, Atwood D, Blue L, White ER, Wakefield, AJ. Pediatric vaccines influence primate behavior, and amygdala growth and opioid ligand binding. O-132.8 International Meeting for Autism Research (IMFAR) London, England, May 15-17, 2008

* Wakefield, AJ, Stott CM, Lopresti B, Tomko J, Houser LA, Sackett G, Hewitson L. Pediatric vaccines influence primate behavior, and brain stem volume and opioid ligand binding. P-157.14 International Meeting for Autism Research (IMFAR) London, England, May 15-17, 2008

* Walker SJ, Lobenhofer, EK, Klein E, Wakefield, AJ, Hewitson L. Microarray analysis of GI tissue in a macaque model of the effects of infant vaccination. P-157.16 International Meeting for Autism Research (IMFAR) London, England, May 15-17, 200

* Stott CM, Wakefield AJ. Phenotypic features of pervasive developmental disorder (PDD) following exposure to polyvalent measles-containing vaccine from a UK litigation cohort. P1A.1.11 International Meeting for Autism Research (IMFAR) Boston, Massachusetts, May 5-8, 2005

* The Gut-Brain Axis in Childhood Developmental Disorders: Viruses and Vaccines. Wakefield AJ., Collins I., Ashwood P. Invited chapter in Infectious Disease and Neuropsychiatric Disorders Chapter 21, pp 198-206. Ed. S.H. Fatemi

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