Evidence females make new eggs
Findings challenge long-held dogma on reproduction
Rick Weiss, Washington Post
Thursday, March 11, 2004
--------------------------------------------------------------------------------
For more than half a century textbooks have taught that female mammals -- be they mice, cows or women -- are born with all the eggs they will ever have. The result is one of the great sexual disparities: Males, who make fresh sperm daily, can sire children at virtually any age, while females gradually deplete their limited supply of eggs to the ticking of the cursed biological clock.
Now Harvard researchers have come to the radical conclusion that female mice produce a constant stream of new egg cells as adults -- challenging a central dogma of reproductive biology and raising the heretical possibility that women, too, clandestinely produce fresh eggs for at least the first half of life.
<SNIP>
It may even be possible to transplant into older or chemotherapy-damaged ovaries some egg-producing cells that have been frozen since youth, restoring a woman's lost fertility.
Those options could have profound social and cultural impacts by granting women more freedom with regard to the timing of careers and parenthood. Even if women chose not to have children later in life, an extended period of fertility could have significant health implications. It might delay the onset of heart disease, osteoporosis and other ailments that become more prevalent after menopause while perhaps increasing the risk of other diseases, such as breast cancer, that have been linked to years of exposure to the hormones the ovaries churn out.
http://www.sfgate.com/cgi-bin/article.cgi?file=/c/a/2004/03/11/MNGPV5IGBO1.DTL